paisano (py-SAH-no) noun 1. A pal, buddy. 2. A fellow countryman; a compatriot. [From Spanish paisano, from French paysan, from Latin pagus (district). Ultimately from the Indo-European root pag- (to fasten) that is also the source of peace, pacify, pact, travel, compact, pagan, and peasant.] -Anu... Sign in to see full entry.